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tetrahydrofolate biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate 2.5.1.15 dihydropteroate synthase

L-glutamate + 7,8-dihydropteroate + ATP <=> H+ + 7,8-dihydrofolate + phosphate + ADP 6.3.2.12 dihydrofolate synthase
6.3.2.17 tetrahydrofolate synthase


tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase




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